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As seen in Fig. 5E, a significant suppression of aB crystallin was achieved by siRNA silencing

saccharometabolism inhibitor May 10, 2017 0 Comments

o elucidate the relative insensitivity of rKir1.1 channel towards animal toxins. First, rKir1.1 channel had a unique turret structure which formed a narrow pore entryway for animal toxins. Different types…

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As seen in Fig. 5E, a significant suppression of aB crystallin was achieved by siRNA silencing

saccharometabolism inhibitor May 10, 2017 0 Comments

o elucidate the relative insensitivity of rKir1.1 channel towards animal toxins. First, rKir1.1 channel had a unique turret structure which formed a narrow pore entryway for animal toxins. Different types…

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Negative controls were obtained by replacement of primary antiserum with buffer

saccharometabolism inhibitor May 10, 2017 0 Comments

iparum was used for apicoplast immunofluorescence. The immunofluorescence protocol was similar to that reported with a few minor changes. A solution of 4% paraformaldehyde and 0.1% Triton X-100 was used…

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We first optimized the conditions for cell transfection and tested MKP-3 expression

saccharometabolism inhibitor May 9, 2017 0 Comments

ssary to reliably define hit compounds in the context of a highthroughput screen using the assay conditions reported in this study. Notably, TFEB overexpression resulted in a 3-fold increase in…

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The LNA probes were a gift from Dr Thomas Tuschl’s lab

saccharometabolism inhibitor May 9, 2017 0 Comments

iate Rag2 dependent recombination and Rag2 expression is highest in small resting DPs as seen in pre-T LBL. Indeed, Fli-1 binding sites have been found in the Notch1 promoter in…

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Whether inactivation of ribosomes was another cause of cell death needs further investigation

saccharometabolism inhibitor May 8, 2017 0 Comments

ence reporting measurements of residual activity of three of the alleles tested. The NAG cell activity assay resulted in average readouts of 24686342 FU for wild-type fibroblasts and 131628 FU…

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Furthermore, miR-7 was reported to be down-regulated in glioblastoma and advanced TSCC

saccharometabolism inhibitor May 8, 2017 0 Comments

eparations were incubated with 0.1% toluidine blue at 37uC for 30 min. Cultures were washed extensively with distilled water and photographed. Study Design The CEPs used in this study was…

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Remarkably, over-activation of the BMP pathway is also incompatible with normal lung development

saccharometabolism inhibitor May 5, 2017 0 Comments

from spleen cells of 7 independent MRL+/+ and MRL/lpr mice. We found that the more responsive allele of P2X7R, the P451 isoform, is carried by the MRL genetic background and…

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For fear of losing information, we did not threshold the images as recommended by the protocol

saccharometabolism inhibitor May 5, 2017 0 Comments

nse labeling of distinct populations of interneurons in contrast to only low to moderate levels of labeling in principal neurons like pyramidal cells. In the hippocampal formation, Arg and ADC…

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However, the role of LPA in prostate cancerinduced lymphangiogenesis is still poorly understood

saccharometabolism inhibitor May 4, 2017 0 Comments

no endothelial cell apoptosis. As mentioned previously, our study only examines one time point. It is possible that apoptosis occurred at an earlier time point than our assessment at the…

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