e further examined the role of 8733580 C/EBb in IL-1b-induced IL-6 expression in transfection study using IL-6 promoter-luciferase assay. Consistent with the results from RT-PCR and ELISAs, IL-1b stimulation alone…
burden in JNK1 2/2 mice. MLK3 2/2 mice, a kinase upstream of JNK1, display increased Influenza A burden due to increased epithelial cell survival and viral replication. The reason for…
ann C, Katschke Jr. KJ, Yin J, Helmy KY, Steffek M, et al. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 444: 217220.…
B overexpression in advanced breast carcinoma and breast cancer cell lines. Consistent with upregulation of EZH2 in aggressive cancers, the clustering revealed high expression of EZH2 in cluster 1, which…
A Novel Method to Evaluate CMA in a Single Neuron these results indicate that the lysosomal translocation of GAPDHHT is mainly mediated by CMA and not by macroautophagy. We therefore…
ation, p53 is systematically deregulated " in cancers and other pathologies involving abnormal cell proliferation. P53 is a multifunctional 393-residue protein. The central core domain constitutes a single folded unit…
genous inhibitor of endoplasmic reticulum-associated degradation. J Biol Chem 282: 3390833914. 7. Ye Y, Meyer HH, Rapoport TA The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER…
iomyoma 15198639" versus adjacent normal myometrial tissue are under epigenetic control. We attempted to identify a subset of genes whose differential DNA SKI-II site methylation correlated with differential mRNA expression.…
xpression and IA activity when compared to wt mice. These results are in agreement with those obtained with similar dream2/2 mice. Moreover, kv4.2 deletion in mice alters the expression of…
fected SH-SY5Y cells. Apoptotic Index is the percentage of cells displaying apoptotic nuclei after treatment with STS for 12 h. doi:10.1371/journal.pone.0024473.t001 In further support of the notion that Hsp72 is…