Ation (PSV) and also the T-tube (TT) in patients with and with no heart disease. The aim of this study was to evaluate the effect on heart price variability (HRV) in these groups of patients during PSV and TT. Strategies Patients with (group 1, n = 8) and without having (group two, n = 22) heart disease, under MV for at least 48 hours, were observed in the course of 30 minutes of PSV or TT, within a random order. Variables analyzed have been: APACHE score, length of remain inside the ICU (LOS), and cardiorespiratory variables such as the HR, respiratory price (RR), rapid shallow breathing index (f/VT), maximum inspiratory (PImax) and expiratory (PEmax) stress. Continuous ECG was recorded by the Holter technique. The data of HRV were accomplished by analysis of your frequency domain. For statistical analyses, evaluation of variance and t test have been made use of. The amount of significance was P < 0.05. Results Values for the APACHE score, LOS, PImax and PEmax did not show significant differences comparing groups. The RR was significantly higher during TT than during PSV in group 1 (25 ?6; 20 ?4; P < 0.01), but similar in group 2 (22 ?5; 22 ?5; not significant (NS)). f/VT was significantly higher during TT in relationship to PSV in group 1 (65 ?35; 39 ?17; P < 0.01), but similar in group 2 (49 ?19; 49 ?22; NS). Changes in the RR interval comparing PSV and TT were significantly different in the entire group (0.48 ?55; ?0 ?72; P = 0.02) as well as changes in the HR interval (?.3 ?8; 8 ?12; P < 0.001). Changes in HRV by frequency domain were not significantly different comparing groups 1 and 2 in PSV and TT. The high frequency was in PSV (4 ?21; 0.4 ?11; NS), and in TT (?.64 ?12; 1 ?12; NS). The low frequency was in PSV (?1 ?22; 3 ?14; NS), and in TT (? ?17; 1.8 ?19; NS).SCritical CareMarch 2007 Vol 11 Suppl27th International Symposium on Intensive Care and Emergency MedicineP176 Evaluation of patient parameters that predict success using the SmartCare weaning systemP Jackson, G Mills Royal Hallamshire Hospital, Sheffield, UK Critical Care 2007, 11(Suppl 2):P176 (doi: 10.1186/cc5336) Introduction Our aim was to assess the success of the SmartCare (SC) weaning system, to see what associated factors made a successful wean more likely. SC is a knowledge-based weaning system integrated into the Dr er EvitaXL ventilator, designed to optimise the ventilator settings during weaning so that patients can be weaned as quickly as possible. Methods The first 100 consecutive general ICU patients where SC weaning had been attempted were identified. Patient age, sex, APACHE score, diagnosis, worst FiO2 prior to weaning, duration of ventilation prior to weaning, duration of weaning attempt, need for tracheostomy and duration of stay were collected. The patients were then subdivided into unsuccessful and successful weaning attempts based upon whether they required subsequent ventilatory support during the first 48 hours after their weaning ended. The two groups were then analysed to identify the characteristics of the patients where a PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20800733 thriving SC wean was achieved. Outcomes Immediately after buy UAMC00039 (dihydrochloride) excluding sufferers whose weaning was interrupted by transfer or maybe a choice to withdraw treatment, we had 89 weaning attempts to analyse. These represented 43 profitable (S) and 46 unsuccessful (US) weans. Comparison of imply ?SD ages (S 61 ?14.three years, US 57.three ?16.1 years, P = 0.28) and APACHE scores (S 16.2 ?4.9, US 17.7 ?six.five, P = 0.23) for the two groups showed no key variations. Logistic regression demonstrated that the worst FiO2.