Housing or if they want the paperwork completed for whatever thing that they need, that’s why NIK333 web they’re coming in. (Nurse Practitioner) I think the biggest challenge that I would see would be the drug use actually compromising their health, compromising their compliance with the medications, and increasing their risk for Hepatitis B, Hepatitis C, HIV, if they are not already impacted by it. I feel that with active drug use that is impacting their participation in safe sexual practices, so therefore not only impacting their health, but impacting the health of others in the community as well. (Physician)Sex, drugs and rock roll Provider reports of how this challenge translated into discussion were more procedural. All seven providers in the study said that they address both sex and drug prevention in the context of the typical visit. Most of the time this discussion covered sexual prevention such as condoms, and how drug use might impact HIV medications or health. For example, providers said:Carlberg-Racich (2016), PeerJ, DOI 10.7717/peerj.17/Sex, drugs and rock n’ roll is part of everybody’s appointment at all times, whether you’re using or not using. We actually have, at the end of our progress note, the questions that are part of the prevention for positives protocol that actually goes through safe sexual practices, condom use, is your partner aware of your HIV status, avoiding drugs, alcohol, things that might impact on your sexual activity or the choices you make. . . A common theme that providers often addressed and initiated in conversation with patients was the importance of disclosing their status to sexual partners. They explained: Lately I’ve been talking with patients who have not disclosed their status to their partner, which is of great concern. Which is why perhaps the rates of HIV have not decreased to the way they I-CBP112 structure should in heterosexual relationships. I know that disclosing to people, I think that’s very important to tell them every single time, `you need to disclose your status if you’re having sex with anybody.’ In terms of assessing addiction, very few providers mentioned doing anything specific. Only one provider discussed using a screening tool related to assessing drug and alcohol use, a brief screening tool to assist a patient in determining whether their use may be problematic. This same provider was versed in the Transtheoretical model and Stages of Change, and seemed to already be incorporating a harm reduction approach to some degree, but she was the only provider to report this type of client-centered approach. She said: I think that’s something that has to be repeated over and over and over. You’re assessing where they’re at, and so you just want to bring it up and then keep bringing it up. And then if they’re not interested in stopping, you can think of ways to minimize their chances of having problems and increasing the risk. So I just think it takes a lot of time. I think people will agree generally to a small change rather than disagree. I think they’re more apt to do something small. . . if I say stop drinking today, okay, that’s not gonna happen. But could they be more choosy about when they drink, or what they drink? Then I may have a chance.DISCUSSIONSummary of findings implications for practice and policyIt is clear that the majority of patients could see the benefit of harm reduction interventions (safer injection counseling, safer stimulant use counseling, overdose prevention, and provision of e.Housing or if they want the paperwork completed for whatever thing that they need, that’s why they’re coming in. (Nurse Practitioner) I think the biggest challenge that I would see would be the drug use actually compromising their health, compromising their compliance with the medications, and increasing their risk for Hepatitis B, Hepatitis C, HIV, if they are not already impacted by it. I feel that with active drug use that is impacting their participation in safe sexual practices, so therefore not only impacting their health, but impacting the health of others in the community as well. (Physician)Sex, drugs and rock roll Provider reports of how this challenge translated into discussion were more procedural. All seven providers in the study said that they address both sex and drug prevention in the context of the typical visit. Most of the time this discussion covered sexual prevention such as condoms, and how drug use might impact HIV medications or health. For example, providers said:Carlberg-Racich (2016), PeerJ, DOI 10.7717/peerj.17/Sex, drugs and rock n’ roll is part of everybody’s appointment at all times, whether you’re using or not using. We actually have, at the end of our progress note, the questions that are part of the prevention for positives protocol that actually goes through safe sexual practices, condom use, is your partner aware of your HIV status, avoiding drugs, alcohol, things that might impact on your sexual activity or the choices you make. . . A common theme that providers often addressed and initiated in conversation with patients was the importance of disclosing their status to sexual partners. They explained: Lately I’ve been talking with patients who have not disclosed their status to their partner, which is of great concern. Which is why perhaps the rates of HIV have not decreased to the way they should in heterosexual relationships. I know that disclosing to people, I think that’s very important to tell them every single time, `you need to disclose your status if you’re having sex with anybody.’ In terms of assessing addiction, very few providers mentioned doing anything specific. Only one provider discussed using a screening tool related to assessing drug and alcohol use, a brief screening tool to assist a patient in determining whether their use may be problematic. This same provider was versed in the Transtheoretical model and Stages of Change, and seemed to already be incorporating a harm reduction approach to some degree, but she was the only provider to report this type of client-centered approach. She said: I think that’s something that has to be repeated over and over and over. You’re assessing where they’re at, and so you just want to bring it up and then keep bringing it up. And then if they’re not interested in stopping, you can think of ways to minimize their chances of having problems and increasing the risk. So I just think it takes a lot of time. I think people will agree generally to a small change rather than disagree. I think they’re more apt to do something small. . . if I say stop drinking today, okay, that’s not gonna happen. But could they be more choosy about when they drink, or what they drink? Then I may have a chance.DISCUSSIONSummary of findings implications for practice and policyIt is clear that the majority of patients could see the benefit of harm reduction interventions (safer injection counseling, safer stimulant use counseling, overdose prevention, and provision of e.