Product Name :
STING ligand-1
Description:
STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING.
CAS:
2365039-41-2
Molecular Weight:
523.98
Formula:
C29H27ClFNO5
Chemical Name:
2-[(3S,4S)-2-(4-tert-butyl-3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1-oxo-1,2,3,4-tetrahydroisoquinolin-4-yl]acetic acid
Smiles :
CC(C)(C)C1C=CC(=CC=1Cl)N1[C@@H]([C@@H](CC(O)=O)C2=CC=C(F)C=C2C1=O)C1C=CC2OCCOC=2C=1
InChiKey:
JAIAHSWXASHNQH-CCLHPLFOSA-N
InChi :
InChI=1S/C29H27ClFNO5/c1-29(2,3)22-8-6-18(14-23(22)30)32-27(16-4-9-24-25(12-16)37-11-10-36-24)20(15-26(33)34)19-7-5-17(31)13-21(19)28(32)35/h4-9,12-14,20,27H,10-11,15H2,1-3H3,(H,33,34)/t20-,27+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING.|Product information|CAS Number: 2365039-41-2|Molecular Weight: 523.98|Formula: C29H27ClFNO5|Chemical Name: 2-[(3S,4S)-2-(4-tert-butyl-3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1-oxo-1,2,3,4-tetrahydroisoquinolin-4-yl]acetic acid|Smiles: CC(C)(C)C1C=CC(=CC=1Cl)N1[C@@H]([C@@H](CC(O)=O)C2=CC=C(F)C=C2C1=O)C1C=CC2OCCOC=2C=1|InChiKey: JAIAHSWXASHNQH-CCLHPLFOSA-N|InChi: InChI=1S/C29H27ClFNO5/c1-29(2,3)22-8-6-18(14-23(22)30)32-27(16-4-9-24-25(12-16)37-11-10-36-24)20(15-26(33)34)19-7-5-17(31)13-21(19)28(32)35/h4-9,12-14,20,27H,10-11,15H2,1-3H3,(H,33,34)/t20-,27+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (477.{{Fosamprenavir} MedChemExpress|{Fosamprenavir} Metabolic Enzyme/Protease|{Fosamprenavir} Technical Information|{Fosamprenavir} In stock|{Fosamprenavir} manufacturer|{Fosamprenavir} Cancer} 12 mM; Need ultrasonic).{{MK-1084} MedChemExpress|{MK-1084} Ras|{MK-1084} Epigenetics|{MK-1084} Biological Activity|{MK-1084} References|{MK-1084} manufacturer} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:27017949 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|STING ligand-1 (Compound 18) exhibits functional inhibition of STING mediated cytokine release.|Products are for research use only. Not for human use.|