Product Name :
RWJ 63556

Description:
RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities.

CAS:
190967-35-2

Molecular Weight:
287.33

Formula:
C11H10FNO3S2

Chemical Name:
N-[5-(4-fluorophenoxy)thiophen-2-yl]methanesulfonamide

Smiles :
CS(=O)(=O)NC1=CC=C(OC2C=CC(F)=CC=2)S1

InChiKey:
BEIZIEZPGSIQGR-UHFFFAOYSA-N

InChi :
InChI=1S/C11H10FNO3S2/c1-18(14,15)13-10-6-7-11(17-10)16-9-4-2-8(12)3-5-9/h2-7,13H,1H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Eteplirsen manufacturer

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities.|Product information|CAS Number: 190967-35-2|Molecular Weight: 287.Renilla-Firefly Luciferase Dual Assay Kit Formula 33|Formula: C11H10FNO3S2|Chemical Name: N-[5-(4-fluorophenoxy)thiophen-2-yl]methanesulfonamide|Smiles: CS(=O)(=O)NC1=CC=C(OC2C=CC(F)=CC=2)S1|InChiKey: BEIZIEZPGSIQGR-UHFFFAOYSA-N|InChi: InChI=1S/C11H10FNO3S2/c1-18(14,15)13-10-6-7-11(17-10)16-9-4-2-8(12)3-5-9/h2-7,13H,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32901514 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|RWJ 63556 is a potent inhibitor of leukocyte influx over a period of 24 hr and maintains its in vitro profile on eicosanoids.|In Vivo:|RWJ 63556 (1 mg/kg, i.v.) significantly inhibits the development of SP-induced oedema.|Products are for research use only. Not for human use.|

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