Product Name :
cIAP1 Ligand-Linker Conjugates 15
Description:
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs.
CAS:
1225433-96-4
Molecular Weight:
661.78
Formula:
C37H47N3O8
Chemical Name:
2-[2-(2-aminoethoxy)ethoxy]ethyl (2R)-2-[(2S,3R)-3-([(9H-fluoren-9-yl)methoxy]carbonylamino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoate
Smiles :
CC(C)C[C@@H](NC(=O)[C@@H](O)[C@@H](CC1=CC=CC=C1)NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(=O)OCCOCCOCCN
InChiKey:
YRJDBNNKOCUVLA-SXLOSVNLSA-N
InChi :
InChI=1S/C37H47N3O8/c1-25(2)22-33(36(43)47-21-20-46-19-18-45-17-16-38)39-35(42)34(41)32(23-26-10-4-3-5-11-26)40-37(44)48-24-31-29-14-8-6-12-27(29)28-13-7-9-15-30(28)31/h3-15,25,31-34,41H,16-24,38H2,1-2H3,(H,39,42)(H,40,44)/t32-,33-,34+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Troglitazone Epigenetic Reader Domain
Shelf Life:
≥12 months if stored properly.Lobaplatin Data Sheet
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32644678
Additional information:
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs.|Product information|CAS Number: 1225433-96-4|Molecular Weight: 661.78|Formula: C37H47N3O8|Chemical Name: 2-[2-(2-aminoethoxy)ethoxy]ethyl (2R)-2-[(2S,3R)-3-([(9H-fluoren-9-yl)methoxy]carbonylamino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoate|Smiles: CC(C)C[C@@H](NC(=O)[C@@H](O)[C@@H](CC1=CC=CC=C1)NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(=O)OCCOCCOCCN|InChiKey: YRJDBNNKOCUVLA-SXLOSVNLSA-N|InChi: InChI=1S/C37H47N3O8/c1-25(2)22-33(36(43)47-21-20-46-19-18-45-17-16-38)39-35(42)34(41)32(23-26-10-4-3-5-11-26)40-37(44)48-24-31-29-14-8-6-12-27(29)28-13-7-9-15-30(28)31/h3-15,25,31-34,41H,16-24,38H2,1-2H3,(H,39,42)(H,40,44)/t32-,33-,34+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Itoh Y, et al. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc. 2010 Apr 28;132(16):5820-6.Products are for research use only. Not for human use.|