Product Name :
PLX4720
Sequence:
Purity:
≥99% (HPLC)
Molecular Weight:
413.8
Solubility :
Soluble in DMSO (83mg/ml) or ethanol (1mg/ml).{{21679-14-1} medchemexpress|{21679-14-1} Protocol|{21679-14-1} In Vivo|{21679-14-1} custom synthesis}
Appearance:
Beige powder.
Use/Stability :
As indicated on product label or CoA when stored as recommended.
Description:
Potent and selective B-Raf V600E inhibitor Equally potent to c-Raf-1 (Y340D and Y341D mutations), and shows 10-fold selectivity for B-Raf V600E over wild-type B-Raf.{{1612838-76-2} web|{1612838-76-2} Technical Information|{1612838-76-2} References|{1612838-76-2} manufacturer}
CAS :
918505-84-7
Solubility:
Soluble in DMSO (83mg/ml) or ethanol (1mg/ml).PMID:29494117
Formula:
C17H14ClF2N3O3S
Additional Information :
| Alternative Name N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide | Appearance Beige powder. | CAS 918505-84-7 | Couple Target Raf | Couple Type Inhibitor | Formula C17H14ClF2N3O3S | Identity Determined by EM-MS, NMR | MW 413.8 | Purity ≥99% (HPLC) | Solubility Soluble in DMSO (83mg/ml) or ethanol (1mg/ml). | Unit of Measure (UM) mg