Product Name :
K-252b
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
453.5
Solubility :
Soluble in DMSO (1mg/ml) or dimethyl formamide (1mg/ml).
Appearance:
White solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at 0-4°C. Stock solutions are stable for up to 3 months at -20°C.
Description:
PKC inhibitor General, cell permeable protein kinase inhibitor. Acts by binding to the ATP binding domain of the kinase.{{1154028-82-6} medchemexpress|{1154028-82-6} Purity & Documentation|{1154028-82-6} In Vivo|{1154028-82-6} custom synthesis} Potent inhibitor of Ca2+/calmodulin kinase II.{{590368-25-5} site|{590368-25-5} Technical Information|{590368-25-5} In Vitro|{590368-25-5} manufacturer} Inhibits myosin light chain kinase (MLCK; Ki=0.147µM), cAMP- dependent protein kinase (PKA; Ki=0.09µM), protein kinase C (PKC; Ki=0.02µM), and cGMP-dependent protein kinase (PKG; Ki=0.1µM).
CAS :
99570-78-2
Solubility:
Soluble in DMSO (1mg/ml) or dimethyl formamide (1mg/ml).PMID:20301387
Formula:
C26H19N3O5
Additional Information :
| Appearance White solid. | CAS 99570-78-2 | Couple Target CaM kinase, MLCK, PKA, PKC, PKG | Couple Type Inhibitor | Formula C26H19N3O5 | MW 453.5 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (1mg/ml) or dimethyl formamide (1mg/ml). | Unit of Measure (UM) mg, µg