Product Name :
ROCK inhibitor-2
Description:
ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively.
CAS:
1127308-52-4
Molecular Weight:
332.40
Formula:
C21H20N2O2
Chemical Name:
N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-ylbenzamide
Smiles :
COC1=CC(=CC=C1)[C@@H](C)NC(=O)C1C=CC(=CC=1)C1C=CN=CC=1
InChiKey:
JRVSFZKYQCETAH-OAHLLOKOSA-N
InChi :
InChI=1S/C21H20N2O2/c1-15(19-4-3-5-20(14-19)25-2)23-21(24)18-8-6-16(7-9-18)17-10-12-22-13-11-17/h3-15H,1-2H3,(H,23,24)/t15-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Osimertinib} site|{Osimertinib} EGFR|{Osimertinib} Protocol|{Osimertinib} In Vivo|{Osimertinib} supplier|{Osimertinib} Cancer}
Shelf Life:
≥12 months if stored properly.{{Recombinant Murine Interleukin-6} site|{Recombinant Murine Interleukin-6} Biological Activity|{Recombinant Murine Interleukin-6} Description|{Recombinant Murine Interleukin-6} manufacturer|{Recombinant Murine Interleukin-6} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23600560
Additional information:
ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively.|Product information|CAS Number: 1127308-52-4|Molecular Weight: 332.40|Formula: C21H20N2O2|Chemical Name: N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-ylbenzamide|Smiles: COC1=CC(=CC=C1)[C@@H](C)NC(=O)C1C=CC(=CC=1)C1C=CN=CC=1|InChiKey: JRVSFZKYQCETAH-OAHLLOKOSA-N|InChi: InChI=1S/C21H20N2O2/c1-15(19-4-3-5-20(14-19)25-2)23-21(24)18-8-6-16(7-9-18)17-10-12-22-13-11-17/h3-15H,1-2H3,(H,23,24)/t15-/m1/s1|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 250 mg/mL (752.11 mM), Need ultrasonic|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.Products are for research use only. Not for human use.|