ation, p53 is systematically deregulated " in cancers and other pathologies involving abnormal cell proliferation. P53 is a multifunctional 393-residue protein. The central core domain constitutes a single folded unit…
genous inhibitor of endoplasmic reticulum-associated degradation. J Biol Chem 282: 3390833914. 7. Ye Y, Meyer HH, Rapoport TA The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER…
iomyoma 15198639" versus adjacent normal myometrial tissue are under epigenetic control. We attempted to identify a subset of genes whose differential DNA SKI-II site methylation correlated with differential mRNA expression.…
xpression and IA activity when compared to wt mice. These results are in agreement with those obtained with similar dream2/2 mice. Moreover, kv4.2 deletion in mice alters the expression of…
fected SH-SY5Y cells. Apoptotic Index is the percentage of cells displaying apoptotic nuclei after treatment with STS for 12 h. doi:10.1371/journal.pone.0024473.t001 In further support of the notion that Hsp72 is…
. The FGFRL1 receptor is shed from cell membranes, binds fibroblast growth factors, and antagonizes FGF signaling in Xenopus embryos. J Biol Chem 285: 21932202. Gringel S, van Bergeijk J,…
fect may well be particular of BM-PC adhesion " for the basement membrane. GSI remedy was shown to substantially lower the expression of integrins alphaNovember Notch Pathway in Bone Marrow…
68), b-actin (Sigma-Aldrich, A5441) and a-spectrin (Millipore, 1622) were performed for 1 h at room temperature, whereas antibodies against REST(Millipore, 07-579), GluA1 (Millipore, AB1504), GluA2 (Millipore, MAB397), GluN1 (Millipore, MAB363),…
en at 24 h inside the case of c-jun (Figure 2A). To ascertain whether or not this transcriptional modulation correlated with increased c-Fos and c-Jun protein expression, CLL cells from…
newal . For the duration of lung improvement in the chick embryo, HoxB transcription things show exclusive patterns of expression inside the mesenchyme of distinct differentiated lung compartments . Consistent…