B overexpression in advanced breast carcinoma and breast cancer cell lines. Consistent with upregulation of EZH2 in aggressive cancers, the clustering revealed high expression of EZH2 in cluster 1, which…
A Novel Method to Evaluate CMA in a Single Neuron these results indicate that the lysosomal translocation of GAPDHHT is mainly mediated by CMA and not by macroautophagy. We therefore…
ation, p53 is systematically deregulated " in cancers and other pathologies involving abnormal cell proliferation. P53 is a multifunctional 393-residue protein. The central core domain constitutes a single folded unit…
genous inhibitor of endoplasmic reticulum-associated degradation. J Biol Chem 282: 3390833914. 7. Ye Y, Meyer HH, Rapoport TA The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER…
iomyoma 15198639" versus adjacent normal myometrial tissue are under epigenetic control. We attempted to identify a subset of genes whose differential DNA SKI-II site methylation correlated with differential mRNA expression.…
xpression and IA activity when compared to wt mice. These results are in agreement with those obtained with similar dream2/2 mice. Moreover, kv4.2 deletion in mice alters the expression of…
fected SH-SY5Y cells. Apoptotic Index is the percentage of cells displaying apoptotic nuclei after treatment with STS for 12 h. doi:10.1371/journal.pone.0024473.t001 In further support of the notion that Hsp72 is…