These data suggest that neddylation inhibits RCAN1 ubiquitination, resulting in the increased RCAN1 levels
In get to examine the protein stability of wild-kind RCAN1 with the conjugationresistant RCAN1 mutant, HEK293 cells ended up transfected with either HA-tagged wild-kind RCAN1 or the RCAN1-3KR mutant, and…