Xylobiose

Product Name : XylobioseDescription:Xylobiose (1,4-β-D-Xylobiose; 1,4-D-Xylobiose) is a disaccharide of xylose monomers with a β-1, 4 bond between monomers.CAS: 6860-47-5Molecular Weight:282.24Formula: C10H18O9Chemical Name: (2R,3R,4R)-2,3,5-trihydroxy-4-{oxy}pentanalSmiles : OC(O1OC(O)(O)1O)(O)(O)C=OInChiKey: SQNRKWHRVIAKLP-RSZZQXBVSA-NInChi : InChI=1S/C10H18O9/c11-1-4(13)7(15)6(2-12)19-10-9(17)8(16)5(14)3-18-10/h1,4-10,12-17H,2-3H2/t4-,5+,6+,7+,8-,9+,10-/m0/s1Purity: ≥98%…

Crocetin

Product Name : CrocetinDescription:Crocetin (β-Crocetin), isolated from Crocus sativus, possesses anti-inflammatory, neuroprotective and antioxidant activity.CAS: 25368-09-6Molecular Weight:342.43Formula: C21H26O4Chemical Name: (2E,4E,6E,8E,10E,12E,14E)-16-methoxy-2,6,11,15-tetramethyl-16-oxohexadeca-2,4,6,8,10,12,14-heptaenoic acidSmiles : COC(=O)/C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C(O)=OInChiKey: DGGQUKOLHQXDLV-QTNXRKSWSA-NInChi : InChI=1S/C21H26O4/c1-16(12-8-14-18(3)20(22)23)10-6-7-11-17(2)13-9-15-19(4)21(24)25-5/h6-15H,1-5H3,(H,22,23)/b7-6+,12-8+,13-9+,16-10+,17-11+,18-14+,19-15+Purity: ≥98% (or refer to…

USP7-IN-3

Product Name : USP7-IN-3Description:USP7-IN-3 (Compound 5) is a potent and selective allosteric ubiquitin-specific protease 7 (USP7) inhibitor.CAS: 2202738-42-7Molecular Weight:568.59Formula: C29H31F3N6O3Chemical Name: 3--6-({4-hydroxy-1-piperidin-4-yl}methyl)-2-methyl-2H,6H,7H-pyrazolopyrimidin-7-oneSmiles : CN1N=C2C(N=CN(CC3(O)CCN(CC3)C(=O)C(C3C=CC=CC=3)C(F)(F)F)C2=O)=C1C1C=CC(CN)=CC=1InChiKey: RLPQYKGBXQQARM-JOCHJYFZSA-NInChi : InChI=1S/C29H31F3N6O3/c1-36-26(21-9-7-19(16-33)8-10-21)24-25(35-36)27(40)38(18-34-24)17-28(41)11-13-37(14-12-28)23(39)15-22(29(30,31)32)20-5-3-2-4-6-20/h2-10,18,22,41H,11-17,33H2,1H3/t22-/m1/s1Purity: ≥98% (or refer…

MEK inhibitor

Product Name : MEK inhibitorDescription:MEK inhibitor is a potent MEK inhibitor with antitumor potency.CAS: 334951-92-7Molecular Weight:426.51Formula: C26H26N4O2Chemical Name: 3-phenyl}imino)(phenyl)methyl]-2-hydroxy-N-methyl-1H-indole-6-carboxamideSmiles : CNC(=O)C1=CC2NC(O)=C(C(=NC3=CC(CN(C)C)=CC=C3)C3C=CC=CC=3)C=2C=C1InChiKey: UPICVLXBXZXYIE-ZZIIXHQDSA-NInChi : InChI=1S/C26H26N4O2/c1-27-25(31)19-12-13-21-22(15-19)29-26(32)23(21)24(18-9-5-4-6-10-18)28-20-11-7-8-17(14-20)16-30(2)3/h4-15,29,32H,16H2,1-3H3,(H,27,31)/b28-24+Purity: ≥98% (or refer to the Certificate…

Baimaside

Product Name : BaimasideDescription:Quercetin 3-beta-sophoroside is isolated from the flowers of A. venetum, is an scavengers of superoxide anions.CAS: 18609-17-1Molecular Weight:626.52Formula: C27H30O17Chemical Name: 2-(3,4-dihydroxyphenyl)-3-{oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5,7-dihydroxy-4H-chromen-4-oneSmiles : OC1C=C2OC(=C(O3O(CO)(O)(O)3O3O(CO)(O)(O)3O)C(=O)C2=C(O)C=1)C1=CC(O)=C(O)C=C1InChiKey: RDUAJIJVNHKTQC-UJECXLDQSA-NInChi : InChI=1S/C27H30O17/c28-6-14-17(34)20(37)22(39)26(41-14)44-25-21(38)18(35)15(7-29)42-27(25)43-24-19(36)16-12(33)4-9(30)5-13(16)40-23(24)8-1-2-10(31)11(32)3-8/h1-5,14-15,17-18,20-22,25-35,37-39H,6-7H2/t14-,15-,17-,18-,20+,21+,22-,25-,26+,27+/m1/s1Purity: ≥98%…

Thiol-C9-PEG5-acid

Product Name : Thiol-C9-PEG5-acidDescription:Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: Molecular Weight:452.65Formula: C22H44O7SChemical Name: 27-sulfanyl-4,7,10,13,16-pentaoxaheptacosanoic acidSmiles : OC(=O)CCOCCOCCOCCOCCOCCCCCCCCCCCSInChiKey: SCWOQJXEVJAGMQ-UHFFFAOYSA-NInChi : InChI=1S/C22H44O7S/c23-22(24)10-12-26-14-16-28-18-20-29-19-17-27-15-13-25-11-8-6-4-2-1-3-5-7-9-21-30/h30H,1-21H2,(H,23,24)Purity: ≥98%…

Glycocyamine-d2

Product Name : Glycocyamine-d2Description:Product informationCAS: 1173020-63-7Molecular Weight:119.12Formula: C3H7N3O2Chemical Name: 2-(H)acetic acidSmiles : C()(N=C(N)N)C(O)=OInChiKey: BPMFZUMJYQTVII-DICFDUPASA-NInChi : InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)/i1D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

Enecadin

Product Name : EnecadinDescription:Enecadin is a neuroprotective agent extracted from patent US 8623823 B2.CAS: 259525-01-4Molecular Weight:357.46Formula: C21H28FN3OChemical Name: 4-(4-fluorophenyl)-2-methyl-6-{oxy}pyrimidineSmiles : CC1N=C(C=C(N=1)OCCCCCN1CCCCC1)C1C=CC(F)=CC=1InChiKey: SZSHJTJCJOWMHM-UHFFFAOYSA-NInChi : InChI=1S/C21H28FN3O/c1-17-23-20(18-8-10-19(22)11-9-18)16-21(24-17)26-15-7-3-6-14-25-12-4-2-5-13-25/h8-11,16H,2-7,12-15H2,1H3Purity: ≥98% (or refer to the Certificate…

Propargyl-PEG1-SS-alcohol

Product Name : Propargyl-PEG1-SS-alcoholDescription:Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).CAS: 1391914-41-2Molecular Weight:192.30Formula: C7H12O2S2Chemical Name: 2-{disulfanyl}ethan-1-olSmiles : C#CCOCCSSCCOInChiKey: WFZUBJGVOIBKLI-UHFFFAOYSA-NInChi : InChI=1S/C7H12O2S2/c1-2-4-9-5-7-11-10-6-3-8/h1,8H,3-7H2Purity:…

HO-PEG13-OH

Product Name : HO-PEG13-OHDescription:HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 17598-96-8Molecular Weight:590.70Formula: C26H54O14Chemical Name: 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diolSmiles : OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOInChiKey: AKWFJQNBHYVIPY-UHFFFAOYSA-NInChi : InChI=1S/C26H54O14/c27-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-25-26-40-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-28/h27-28H,1-26H2Purity: ≥98% (or…

Gly-PEG3-endo-BCN

Product Name : Gly-PEG3-endo-BCNDescription:Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 2354291-37-3Molecular Weight:453.57Formula: C23H39N3O6Chemical Name: non-4-yn-9-yl]methyl N-ethoxy}ethoxy)propyl]carbamateSmiles : NCC(=O)NCCCOCCOCCOCCCNC(=O)OCC12CCC#CCC21InChiKey: MZZHRBCWKALCAE-WCRBZPEASA-NInChi : InChI=1S/C23H39N3O6/c24-17-22(27)25-9-5-11-29-13-15-31-16-14-30-12-6-10-26-23(28)32-18-21-19-7-3-1-2-4-8-20(19)21/h19-21H,3-18,24H2,(H,25,27)(H,26,28)/t19-,20+,21?Purity: ≥98%…

Ald-Ph-amido-PEG11-NH-Boc

Product Name : Ald-Ph-amido-PEG11-NH-BocDescription:Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).CAS: 1245813-70-0Molecular Weight:776.91Formula: C37H64N2O15Chemical Name: tert-butyl N-{35--3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-yl}carbamateSmiles : CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)C1C=CC(=CC=1)C=OInChiKey: RDSLXILMKJRJBU-UHFFFAOYSA-NInChi :…

Glucosinalbate potassium

Product Name : Glucosinalbate potassiumDescription:Glucosinalbate potassium is a natural product that can be isolated from Arabidopsis thaliana.CAS: 16411-05-5Molecular Weight:463.52Formula: C14H18KNO10S2Chemical Name: potassium (Z)-sulfanyl}ethylidene]amino sulfateSmiles : .S(=O)(=O)O/N=C(/CC1=CC=C(O)C=C1)\S1O(CO)(O)(O)1OInChiKey: LAMNAIMKLRHPRP-UDQIAKBUSA-MInChi : InChI=1S/C14H19NO10S2.K/c16-6-9-11(18)12(19)13(20)14(24-9)26-10(15-25-27(21,22)23)5-7-1-3-8(17)4-2-7;/h1-4,9,11-14,16-20H,5-6H2,(H,21,22,23);/q;+1/p-1/b15-10-;/t9-,11-,12+,13-,14+;/m1./s1Purity: ≥98%…

6-Hydroxy-4-methylcoumarin

Product Name : 6-Hydroxy-4-methylcoumarinDescription:6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity.CAS: 2373-31-1Molecular Weight:176.17Formula: C10H8O3Chemical Name: 6-hydroxy-4-methyl-2H-chromen-2-oneSmiles : CC1=CC(=O)OC2=CC=C(O)C=C21InChiKey: IRUHWRSITUYICV-UHFFFAOYSA-NInChi : InChI=1S/C10H8O3/c1-6-4-10(12)13-9-3-2-7(11)5-8(6)9/h2-5,11H,1H3Purity: ≥98% (or refer to the…

4-Hydroxyestrone-d4

Product Name : 4-Hydroxyestrone-d4Description:Product informationCAS: 81586-98-3Molecular Weight:290.39Formula: C18H22O3Chemical Name: (3aS,3bR,9bS,11aS)-6,7-dihydroxy-11a-methyl(2,2,8,9-²H₄)-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopentaphenanthren-1-oneSmiles : C1()C23CCC4=C(3CC2(C)C1=O)C()=C()C(O)=C4OInChiKey: XQZVQQZZOVBNLU-RFZGAVBWSA-NInChi : InChI=1S/C18H22O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,19,21H,2-3,5,7-9H2,1H3/t11-,12-,14+,18+/m1/s1/i4D,6D,7D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous…

nTZDpa

Product Name : nTZDpaDescription:Product informationCAS: 118414-59-8Molecular Weight:428.33Formula: C22H15Cl2NO2SChemical Name: 5-chloro-1--3-(phenylsulfanyl)-1H-indole-2-carboxylic acidSmiles : OC(=O)C1=C(SC2C=CC=CC=2)C2=CC(Cl)=CC=C2N1CC1C=CC(Cl)=CC=1InChiKey: VUPOTURDKDMIGQ-UHFFFAOYSA-NInChi : InChI=1S/C22H15Cl2NO2S/c23-15-8-6-14(7-9-15)13-25-19-11-10-16(24)12-18(19)21(20(25)22(26)27)28-17-4-2-1-3-5-17/h1-12H,13H2,(H,26,27)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

N20C hydrochloride

Product Name : N20C hydrochlorideDescription:Product informationCAS: 1177583-87-7Molecular Weight:304.81Formula: C17H21ClN2OChemical Name: 2-acetamide hydrochlorideSmiles : Cl.NC(=O)CNCCC(C1C=CC=CC=1)C1C=CC=CC=1InChiKey: JCJDLPUASJEVRN-UHFFFAOYSA-NInChi : InChI=1S/C17H20N2O.ClH/c18-17(20)13-19-12-11-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15;/h1-10,16,19H,11-13H2,(H2,18,20);1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature…

Aminoglutethimide

Product Name : AminoglutethimideDescription:Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM.CAS: 125-84-8Molecular Weight:232.28Formula: C13H16N2O2Chemical Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dioneSmiles : CCC1(CCC(=O)NC1=O)C1C=CC(N)=CC=1InChiKey: ROBVIMPUHSLWNV-UHFFFAOYSA-NInChi : InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)Purity: ≥98% (or refer to the Certificate of…

5′-O-(tert-Butyldimethylsilyl)thymidine, 97+%

Product Name : 5'-O-(tert-Butyldimethylsilyl)thymidine, 97+%Synonym: IUPAC Name : 1-methyl}-4-hydroxyoxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dioneCAS NO.:40733-28-6Molecular Weight : Molecular formula: C16H28N2O5SiSmiles: CC1=CN(2C(O)(CO(C)(C)C(C)(C)C)O2)C(=O)NC1=ODescription: 5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate.S1p receptor agonist 1 Ganciclovir PMID:24633055 MedChemExpress (MCE) offers…

Sisomicin sulfate, 90%

Product Name : Sisomicin sulfate, 90%Synonym: IUPAC Name : (2R,3R,4R,5R)-2-{oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; sulfuric acidCAS NO.Hoechst 33342 :53179-09-2Molecular Weight : Molecular formula: C19H39N5O11SSmiles: OS(O)(=O)=O.Pozelimab CN1(O)(O2(N)C(N)(O3OC(CN)=CC3N)2O)OC1(C)ODescription: PMID:23008002 MedChemExpress (MCE) offers a wide range of…

Fexofenadine hydrochloride

Product Name : Fexofenadine hydrochlorideSynonym: IUPAC Name : hydrogen 2-(4-{1-hydroxy-4-butyl}phenyl)-2-methylpropanoic acid chlorideCAS NO.:153439-40-8Molecular Weight : Molecular formula: C32H40ClNO4Smiles: .Biotin Hydrazide .Ferritin heavy chain/FTH1 Protein, Human CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1Description: Fexofenadine hydrochloride is used…

: 5GCTGATGCCAATGACGATGA-3 for ABCG8; forward: 5-CCGTGGCTTTTTCTTCTCTCA-3 and reverse: 5GCATTCGGAACAGTGCAACA-3; for SCD-1; forward

: 5GCTGATGCCAATGACGATGA-3 for ABCG8; forward: 5-CCGTGGCTTTTTCTTCTCTCA-3 and reverse: 5GCATTCGGAACAGTGCAACA-3; for SCD-1; forward: 5-CACCCCCTCGTTGAAAACCT-3 and reverse: 5CCTTAGCCAGCTCTTCCAGATC-3 for LDLR; forward: 5-GCATTCGGAACAGTGCAACA-3 and reverse: 5TCATGAATGGTGCCCACATC-3 for SR-B1; and forward: 5-GAAGACACCAGTAGACTCCACGACATA-3 and reverse:…

.K.,.K. Conflict of Interest: Noconflictofinterestwasdeclaredbytheauthors. Financial Disclosure: The authors declared

.K.,.K. Conflict of Interest: Noconflictofinterestwasdeclaredbytheauthors. Monetary Disclosure: The authors declared that this study has received no financialsupport.magnesium levels of two.53.5 mg/dL in comparison with the controlgroup(thisroughlycorrelatesto1.04.21mmol/Lwhen convertedtoSIunitusingtheconversionfactor0.4114).Interestingly, they didn't use…

SofthenormalizedFdvaluesexhibitedasingle- eak p curveforP. tabulaeformis,whileH. rhamnoidesexhibitedamultipeakcurve just before andafter rainfall (Figures

SofthenormalizedFdvaluesexhibitedasingle- eak p curveforP. tabulaeformis,whileH. rhamnoidesexhibitedamultipeakcurve ahead of andafter rainfall (Figures4a,b). ThenormalizedFd values had been approximately zero in between 0:00 and 6:00hr, and it increasedshortlyaftersunrise.ThenormalizedFdvaluesdecreasedtoa relativelylowerlevelaftersunsetandgraduallyreachedtheminimum aftermidnight.ThediurnalcoursesofthenormalizedFdforP. tabulaeformisremainedrelativelystablebeforeandafterrainfalleventsinthe 3 periods…

Bp1-/Trif-/WT 7 11 24 0 16 12 0 14 27Genotype of offspring Genotype of parentsTrifwt-/Ripk

Bp1-/Trif-/WT 7 11 24 0 16 12 0 14 27Genotype of offspring Genotype of parentsTrifwt-/Ripk1mRHIM/mRHIMWTNature. Author manuscript; readily available in PMC 2018 January 05.Ripk1mRHIM/wt Ripk1mRHIM/wt Ripk1mRHIM/mRHIM0LineRipk1wt/mRHIMTrifwt/Ripk1wt/mRHIMTrifwt-/-Ripk1wt/mRHIMTrifwt/Ripk1wt/mRHIMTrif-/-Europe PMC Funders Author ManuscriptsPageEurope…

G. 2, 2-chloropodophyllotoxin (four), 2,6-dichloropodophyllotoxin (5), and 2-bromopodophyllotoxin (6) had been firstly Angiopoietin-2 Protein MedChemExpress

G. 2, 2-chloropodophyllotoxin (four), 2,6-dichloropodophyllotoxin (5), and 2-bromopodophyllotoxin (6) had been firstly Angiopoietin-2 Protein MedChemExpress obtained as described previouslyG. two, 2-chloropodophyllotoxin (4), two,6-dichloropodophyllotoxin (five), and 2-bromopodophyllotoxin (6) have been firstly…

Ronments(Table3)(femalemovement, malegenotype nvironment:two(df=1)=0.013,p = .91).Forfemale movement, therewas, having said thatRonments(Table3)(femalemovement, malegenotype nvironment:two(df=1)=0.013,p = .91).Forfemale movement,

Ronments(Table3)(femalemovement, malegenotype nvironment:two(df=1)=0.013,p = .91).Forfemale movement, therewas, having said thatRonments(Table3)(femalemovement, malegenotype nvironment:two(df=1)=0.013,p = .91).Forfemale movement, therewas, nevertheless, an interaction among male genotypeandtime(Table3)(femalemovement,malegenotype ime:2 (df=1)=16.99,p = .0002). Locomotion in D. melanogaster…

Ts and 1,3-benzenedicarboxylic acid, 4,four -[1,4,10trioxa-7,13-diazacyclopentadecane-7,13-diylbis(5-methoxy-6,12benzofurandiyl)]bis-, tetrakis[(acetyloxy)methyl] ester-detected [Na ]i significantly improved in cells overexpressing

Ts and 1,3-benzenedicarboxylic acid, 4,four -bis-, tetrakis ester-detected i significantly improved in cells overexpressing NCX1.four as well as ER Ca2 content material. This latter effect was prevented by tetrodotoxin. In…

Ypertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy MildYpertrophic cardiomyopathy No None Hypertrophic

Ypertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy MildYpertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy Mild Hypertrophic cardiomyopathy Mild Hypertrophic cardiomyopathy MilddYesNoYesNoNoc NAAnimal fat-free diet…

Ypertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy MildYpertrophic cardiomyopathy No None Hypertrophic

Ypertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy MildYpertrophic cardiomyopathy No None Hypertrophic cardiomyopathy Mild NA Hypertrophic cardiomyopathy Mild Hypertrophic cardiomyopathy Mild Hypertrophic cardiomyopathy MilddYesNoYesNoNoc NAAnimal fat-free diet…